Author

Robert Anthony Huddart

Institute of Cancer ResearchORCID 0000-0003-3604-1990Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ananya ChoudhuryiD· 3 shared Emma HalliD· 3 shared Nicholas David JamesiD· 3 shared Alexander R. BakeriD· 2 shared Catharine WestiD· 2 shared Conrado Guerrero QuilesiD· 2 shared Kimberley Jayne Reeves· 2 shared Luisa Vanesa BiolattiiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Ananya ChoudhuryORCID

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Author profile →

3 papers

Recent·Most cited

Spatially-resolved multimodal profiling identifies functionally-heterogeneous cancer-associated fibroblasts associated with poor radiotherapy outcomes in muscle-invasive bladder cancer.

Amy Burley, Katie O’Fee, Morgane Dromby, Mi Chween Chan, Barry A. Gusterson, Adrian Lärkeryd, Emma Westlund, Priya Narayanan, Chirine Sakr, Tatiany Silveira, Rose Foster, Mikel Portillo, Marc Rabionet Diaz, Tom Lund, Alan A. Melcher, , Anna Clare Wilkins

This study identifies functionally heterogeneous cancer-associated fibroblasts in muscle-invasive bladder cancer linked to poor radiotherapy outcomes.

bioRxiv · Sep 22, 2026 · PreprintCancer Biology

Fractionated radiation alters the extracellular matrix produced by muscle-invasive bladder cancer cells

Conrado Guerrero Quiles, S. Fahy, Michalina Bartak, Gonzalez A. Julia, Elizabeth E. Powel, Rachel Reed, Kimberley Jayne Reeves, Alexander R. Baker, Peter Hoskin, Nicholas David James, Emma Hall, Robert Anthony Huddart, Núria Porta, Catharine West, Luisa Vanesa Biolatti, Ananya Choudhury

This study shows fractionated radiation changes the extracellular matrix (ECM) composition in muscle-invasive bladder cancer, with ECM-related genes linked to poor prognosis.

bioRxiv · Apr 8, 2025 · PreprintCancer Biology

Hypoxia-induced extracellular matrix changes are conserved in cancer and directly impact radiotherapy benefit

Conrado Guerrero Quiles, A. Julia Gonzalez, Arnaud Foussat, Argyro Olympitis, Taha Lodhi, Vicky Smith, Mark Reardon, Rekaya Shabbir, Sapna Lunj, Kimberley Jayne Reeves, Alexander R. Baker, Michael Eyers, Gayle B. Marshall, Timothy Smith, Peter Hoskin, , Catharine West

The paper identifies hypoxia-induced ECM changes across cancers and shows they predict radiotherapy benefit.

bioRxiv · Apr 4, 2025 · PreprintCancer Biology