Author

Conrado Guerrero Quiles

University of ManchesterORCID 0000-0002-9348-3130Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ananya ChoudhuryiD· 3 shared Catharine WestiD· 3 shared Kimberley Jayne Reeves· 3 shared Luisa Vanesa BiolattiiD· 3 shared Peter HoskiniD· 3 shared Alexander R. BakeriD· 2 shared Emma HalliD· 2 shared Nicholas David JamesiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Ananya ChoudhuryORCID

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Author profile →

4 papers

Recent·Most cited

Whole-genome pre-amplification as a viable approach for genomic screening of FFPE-derived DNA samples

Conrado Guerrero Quiles, Taha Lodhi, Robert Sellers, Sudhakar Sahoo, John Weightman, Wolfgang Breitwieser, Diego Sánchez Martinez, Matej Bartak, Amen Shamim, Steve Lyons, Kimberley Jayne Reeves, Rachel Reed, Peter Hoskin, Catharine West, Laura J. Forker, , Luisa Vanesa Biolatti

This study evaluates DLMDA for improving DNA yield from FFPE samples but finds it reduces CNA sensitivity.

bioRxiv · Mar 29, 2026 · PreprintMolecular Biology

In situ programming of intratumoural stem cell-like memory CD8+ T cells enables durable antitumour immunity in immunosuppressive tumours

Xiaomeng Wang, Ana Vitlić, Erminia Romano, Rachel Scholey, Leo A. H. Zeef, Conrado Guerrero Quiles, Antonia Banyard, Richard C. Walshaw, Tim Illidge, Jamie Honeychurch

This study shows that activating pattern recognition receptors in tumors enhances stem cell-like memory CD8 T cells, improving antitumor immunity when combined with radiation in lung and bladder cancer models.

bioRxiv · Feb 7, 2026 · PreprintCancer Biology

Fractionated radiation alters the extracellular matrix produced by muscle-invasive bladder cancer cells

Conrado Guerrero Quiles, S. Fahy, Michalina Bartak, Gonzalez A. Julia, Elizabeth E. Powel, Rachel Reed, Kimberley Jayne Reeves, Alexander R. Baker, Peter Hoskin, Nicholas David James, Emma Hall, Robert Anthony Huddart, Núria Porta, Catharine West, Luisa Vanesa Biolatti, Ananya Choudhury

This study shows fractionated radiation changes the extracellular matrix (ECM) composition in muscle-invasive bladder cancer, with ECM-related genes linked to poor prognosis.

bioRxiv · Apr 8, 2025 · PreprintCancer Biology

Hypoxia-induced extracellular matrix changes are conserved in cancer and directly impact radiotherapy benefit

Conrado Guerrero Quiles, A. Julia Gonzalez, Arnaud Foussat, Argyro Olympitis, Taha Lodhi, Vicky Smith, Mark Reardon, Rekaya Shabbir, Sapna Lunj, Kimberley Jayne Reeves, Alexander R. Baker, Michael Eyers, Gayle B. Marshall, Timothy Smith, Peter Hoskin, , Catharine West

The paper identifies hypoxia-induced ECM changes across cancers and shows they predict radiotherapy benefit.

bioRxiv · Apr 4, 2025 · PreprintCancer Biology