Saeid Ghavami

This paper identifies treatment-resilient lipid remodeling in TMZ-resistant glioblastoma cells, showing that resistance is linked to coordinated changes in multiple lipid families rather than single species.

This study shows that BCL2L13 downregulation in NSCLC promotes metastasis by impairing mitophagy and enhancing epithelial plasticity and anoikis tolerance.

The paper identifies shared microbial dysbiosis in OPMD and OSCC across cohorts and evaluates the transportability of an OSCC classifier, finding limited diagnostic utility.

The paper integrates systems biology and machine learning to analyze bacterial signaling networks in OSCC, identifies key nodes, and designs multi-target ligands for the MAPK1-STAT3-mTOR axis.

This study shows that autophagy and cholesterol metabolism are remodeled in glioma progression and TMZ resistance, with impaired autophagy linked to reduced cholesterol synthesis and altered lipid profiles.

The paper uses hierarchical machine learning to identify topological differences in autophagy networks between pathogenic and commensal oral bacteria in OSCC.

This study examines sex-specific differences in autophagy and mitophagy in Alzheimer's disease using mouse models and machine learning to predict cellular outcomes.

This study shows that 40 Hz flickering light improves cognition and mitochondrial function in a rat model of Alzheimer's disease.

This study identifies BCL2L13 as a regulator of autophagy and ceramide metabolism in glioblastoma, showing distinct effects on metabolic pathways in TMZ-resistant and sensitive cells.

This paper introduces a non-fluorescent immunohistochemistry method to measure autophagy flux, demonstrating its cost-effectiveness and applicability to clinical settings.

This study shows that T2R14 downregulates autophagy flux in gingival epithelial cells and that S. mutans CSP-1 induces calcium release dependent on T2R14 and autophagy protein 7.

This study develops a method to measure autophagy flux in TMZ-resistant glioblastoma cells using imaging and biochemical assays, providing insights into chemoresistance mechanisms.

The paper evaluates autophagy in conjunctival fibroblasts using immunocytochemistry, immunoblotting, and qPCR to understand its role in vernal keratoconjunctivitis.

This study evaluates how matrix stiffness affects autophagosome formation and apoptosis in embryonal rhabdomyosarcoma cells using GelMA hydrogels.

The paper uses lipidomics to investigate the role of lipids and their interaction with autophagy in lung cancer metastasis.

This study develops methods to assess autophagy in Leishmania major parasites using transmission electron microscopy and flow cytometry with acridine orange dye.

The paper characterizes T2R14-dependent autophagy in gingival epithelial cells using western blot and flow cytometry to assess autophagy flux.