Sijia He

This study identifies a non-enzymatic role of ABHD6 in regulating selective hepatic insulin resistance and MASLD through interaction with the Akt-FoxO1 axis.

This study investigates the relationship between sulfatide deficiency, neuroinflammation, and lipid dyshomeostasis in a mouse model, showing Trem2's role in microglia-mediated neuroinflammation but not astrogliosis or myelin lipid disruption.

imply improves cell-type deconvolution by using personalized reference panels, showing reduced bias and better alignment with biological facts in real data.

This study shows that deleting cGAS in microglia reduces amyloid-β plaque formation and cognitive impairment in Alzheimer's disease models.

This study shows that CNS sulfatide deficiency causes sex-dependent metabolic changes in aging, with females showing more severe metabolic disruption than males.