Comparison of CRISPR-Cas-based knockdown of endogenous mRNA in sensory neurons
Andrea Meulenberg, Macarena Pavez, Emma K. Gowing, David Mayo-Muñoz, Nils Birkholz, Graceallah Suhono, Peter C. Fineran, Robert D. Fagerlund, Laura F. Gumy
This study compares CRISPR-Cas systems for RNA knockdown in rat sensory neurons, finding hfCas13d provides robust gene silencing with minimal toxicity.
The CRISPR Journal · Sep 23, 2026Peer-reviewedCell Biology