Shang Ma

This study identifies GAA accumulation in gliomas as a driver of neuronal activity and tumor growth, linking cancer metabolism to neuroscience through GABAA receptor activation.

This study shows that enhanced PIEZO1 function in sickle erythrocytes contributes to hemolysis and inflammation in SCD, and that EPA diet reduces PIEZO1 activity and ameliorates disease symptoms.

The paper shows that a gain-of-function PIEZO2 mutation in sensory neurons causes joint contractures in mice, and that Botox and dietary fatty acids can alleviate these defects.