Valeria Vásquez

This study identifies PIEZO1-mediated mechanosensation as a mechanism linking aging to bladder dysfunction and proposes dietary intervention as a non-invasive strategy.

This study shows that enhanced PIEZO1 function in sickle erythrocytes contributes to hemolysis and inflammation in SCD, and that EPA diet reduces PIEZO1 activity and ameliorates disease symptoms.

This study identifies gex-3 as a suppressor of a PIEZO-1 gain-of-function mutation in C. elegans, revealing a role for the cytoskeleton in regulating PIEZO channel activity.

The paper shows that a gain-of-function PIEZO2 mutation in sensory neurons causes joint contractures in mice, and that Botox and dietary fatty acids can alleviate these defects.