Camila Kofman

This study uses community science and experimental screening to design mutant ribosomes with improved protein synthesis and cell growth in vitro and vivo.

The paper designs and selects ribosomal active site mutants with high activity using a computational approach to overcome limitations in rRNA modification.

This paper improves genomically recoded E. coli strains for producing proteins with non-canonical amino acids by optimizing nuclease and protease function and introducing an inducible T7 RNA polymerase cassette.