Author

Xiaohui Zhu

Ministry of Education of the People's Republic of ChinaORCID 0000-0003-3869-5437Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Jie QiaoiD· 3 shared Liying YaniD· 3 shared Ming YangiD· 2 shared Zhiqiang YaniD· 2 shared Bailong XiaoiD· 1 shared Cuiling Lu· 1 shared Haojie He· 1 shared Hongyan Guo· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersPhysiology

Jie QiaoORCID

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3 papers

Recent·Most cited

The fetal hydrops-associated single-residue mutation L322P abolishes mechanical but not chemical activation of the PIEZO1 ion channel

Jinghui Jiang, Wei Guo, Xudong Chen, Yubo Wang, Xiaohui Zhu, Liying Yan, Jie Qiao, Bailong Xiao

The paper identifies a mutation in PIEZO1 that abolishes mechanical activation but not chemical activation, showing a direct link between mechanosensitivity and fetal hydrops.

bioRxiv · Feb 18, 2025 · PreprintPhysiology

Single-cell multiomics sequencing reveals the functional regulatory landscape of early embryos

Yang Wang, Peng Yuan, Zhiqiang Yan, Ming Yang, Ying Huo, Yanli Nie, Xiaohui Zhu, Jie Qiao, Liying Yan

This study develops a single-cell multiomics sequencing method to analyze epigenetic and transcriptional dynamics in mouse preimplantation embryos, revealing regulatory networks and lineage specification mechanisms.

Nature Communications · Feb 23, 2021Peer-reviewedDevelopmental Biology

Transcriptome Landscape of Human Oocytes and Granulosa Cells Throughout Folliculogenesis

Yaoyao Zhang, Zhiqiang Yan, Qingyuan Qin, Vicki Nisenblat, Yang Yu, Tianren Wang, Cuiling Lu, Ming Yang, Shuo Yang, Ying Yao, Xiaohui Zhu, Xi Xia, Yujiao Dang, Yixin Ren, Peng Yuan, , Liying Yan

This study profiles the transcriptomes of human oocytes and granulosa cells across folliculogenesis stages, identifying stage-specific genes, cell interactions, and differences from mouse oocytes.

bioRxiv · Mar 23, 2018 · PreprintCell Biology