Ludovic Orlando

This study evaluates epigenetic clocks for age estimation in ancient human DNA, finding they are unreliable for continuous age-at-death but accurate for sex determination.

The paper reanalyzes ancient DNA data from Mazongshan and finds that four specimens previously identified as hinnies are actually donkeys, removing genetic evidence for hinnies at the site.

This study uses a Bayesian mixed-effects molecular clock model to analyze HBV genomic data, revealing declining evolutionary rates and linking viral spread to human migration patterns.

The paper uses archaeological and isotopic analysis to show that domestic horses and donkeys were transported to Jamestown, Virginia in 1606, with evidence of their use and consumption during the 'Starving Time' and the presence of a donkey with mixed European and West African ancestry.

This study uses modern and ancient DNA data to show that Madagascar turtle doves colonized Mauritius and Reunion independently from Madagascar before human arrival, challenging historical accounts of human-induced demographic collapse.

This study presents a hybridization capture system to enrich and detect ancient human pathogens from archaeological samples with minimal sequencing.

This paper identifies a cis-regulatory variant near EDN3 linked to blood pressure regulation and elite racing performance in horses.

The paper improves the equine transcriptome annotation using long-read RNA sequencing, achieving 45% better completeness and enhanced identification of alternative splicing and noncoding genes.

The paper sequences ancient genomes of Sussemionus, re-dating its extinction to the late Holocene and revealing genetic divergence and admixture events in the Equus lineage.

This study analyzes ancient genomes from the Viking Age to understand genetic structure and migration patterns, finding significant foreign gene flow and population differentiation.

This study uses Early Pleistocene dental enamel proteome sequences to resolve the phylogeny of Stephanorhinus, showing it is paraphyletic and requiring systematic revision.

The paper presents an updated horse reference genome, EquCab3, which improves contiguity and composition compared to the previous version, EquCab2.

The paper develops two new SNP arrays for horses, MNEc2M and MNEc670k, and demonstrates their imputation capabilities.

This study improves endogenous DNA recovery from ancient bones and teeth through optimized enzymatic pre-digestion, increasing endogenous DNA content by up to 14 times in teeth.