Dan Shao

A Selective Multivalent NET-Associated Chromatin Neutralizer Resolves Infection-Associated Inflammation in Severe Sepsis

This paper develops a multivalent NET-neutralizer that reduces inflammation in severe sepsis by targeting DNA-histone chromatin complexes while maintaining antibacterial activity.

Therapeutic targeting inflammation linking periodontitis and atherosclerotic comorbidities using cell-free DNA-capturing nanomaterials

This study develops nanomaterials that capture cell-free DNA to reduce inflammation in periodontitis and atherosclerosis by modulating macrophage lipid markers.

Machine learning engineered PoLixNano nanoparticles overcome delivery barriers for nebulized mRNA therapeutics

The paper develops PoLixNano nanoparticles using machine learning to enhance mRNA delivery through nebulization, achieving high transfection efficiency and therapeutic efficacy in animal models.