Author

Vadim S. Korotkov

Helmholtz Centre for Infection ResearchORCID 0000-0003-3970-2483Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Mark BrönstrupiD· 2 shared Abdelhakim BoudriouaiD· 1 shared Alexander Kohler· 1 shared André FleißneriD· 1 shared Antje FliegeriD· 1 shared Antti PosoiD· 1 shared Arun Naini· 1 shared Birte Dowerg· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Mark BrönstrupORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 29, 2025

Itaconate is metabolized to 2-hydroxymethylsuccinate through a CoA-independent degradation pathway in mitochondria

Fangfang Chen, Laura Hadam, Birte Dowerg…·Thekla Cordes

The paper identifies 2-hydroxymethylsuccinate as a product of itaconate metabolism via a CoA-independent pathway and shows tissue-specific degradation routes.

DOI 10.1101/2025.09.29.679238

metabolomicsexperimental assay

𝕏 PostBluesky

MicrobiologyScience AdvancesPeer-reviewedApr 11, 2025

Discovery of a synthetic small molecule targeting the central regulator of Salmonella pathogenicity

Abdelhakim Boudrioua, Joe D. Joiner, Iwan Grin…·Samuel Wagner

The paper identifies a synthetic small molecule, C26, that inhibits HilD, a key regulator of Salmonella secretion systems, thereby preventing bacterial invasion of host cells.

4 citations

bacteria (other)experimental assay

𝕏 PostBluesky