Author

M. Thomas Record

University of Wisconsin–MadisonORCID 0000-0003-3973-7694Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aaron A. HoskinsiD· 1 shared Hao‐Che WangiD· 1 shared Maxwell RectoriD· 1 shared Rahul VivekiD· 1 shared Renxi Li· 1 shared Saeed RoschdiiD· 1 shared Samuel E. ButcheriD· 1 shared Takuma KumeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

Aaron A. HoskinsORCID

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2 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedAug 12, 2026

TDP-43 controls RNA structure through high affinity lattice interactions

Rahul Vivek, Takuma Kume, Saeed Roschdi…·Samuel E. Butcher

This study shows TDP-43 binds to GU repeats with high affinity, prevents pUG fold formation, and reveals an interplay between RNA folding and protein recognition.

1 citation

humanexperimental assay

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BiochemistryBiochemistryPeer-reviewedJun 4, 2025

Evidence for Stepwise Disruption of E. coli RNA Polymerase-{lambda}R Promoter Contacts and Bubble Collapse in Transcription Initiation

Maxwell Rector, Renxi Li, Hao‐Che Wang, M. Thomas Record

The paper investigates stepwise disruption of E. coli RNA polymerase-promoter contacts during transcription initiation using kinetic m-values and activation energies of nucleotide-incorporation steps.

DOI 10.1021/acs.biochem.4c00806

E. coliDNA methylation

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