Samuel E. Butcher

This study shows TDP-43 binds to GU repeats with high affinity, prevents pUG fold formation, and reveals an interplay between RNA folding and protein recognition.

This study identifies sequence and ionic requirements for pUG fold RNA quadruplexes, showing flexibility in nucleotide substitutions and specific ion dependence.

This study investigates the structure, folding kinetics, and dynamics of long poly(UG) RNAs, revealing a dynamic model for segmental register exchange and double pUG fold formation.

This study uses CoSMoS to analyze how RNA modifications and Prp24 influence Lsm2-8 binding dynamics during U6 snRNP assembly in yeast.

The paper identifies a novel RNA quadruplex structure, the pUG fold, that drives gene silencing in C. elegans and is present in human non-coding RNAs.