Ellen Yeh

A genome-wide CRISPR screen in diatoms identifies genes critical for survival under different light conditions, including a novel gene involved in cyclic electron flow.

This paper demonstrates that cryo-ExM overcomes diatom silica barriers to enable high-resolution imaging and comparative cell biology across diverse diatom species.

The paper analyzes genomes of nitrogen-fixing eukaryotes to show that endosymbionts can function as integral cell compartments without significant genetic integration.

This paper identifies MMV1580853 as a fast-acting antimalarial with a mechanism distinct from artemisinin and chloroquine, showing rapid parasite killing in vitro.

The paper identifies mixed alkyl/aryl phosphonates as anti-malarial compounds that inhibit serine hydrolases with low resistance potential.

The paper uses long-read sequencing to show that increased copies of the GCH1 gene are associated with DHODH gene amplification in malaria parasites, suggesting a metabolic interplay between these two drug targets.