Michael Rehli

This study shows that timed STING inhibition reduces gastrointestinal GvHD without affecting GvL in mouse models, suggesting a potential therapeutic strategy for allo-HSCT.

The paper shows that Treg cells use IFNγ and IL-10 to promote intestinal stem cell growth and repair after injury.

This study identifies desaminotyrosine (DAT) as a microbial metabolite that protects against graft-versus-host disease by promoting intestinal regeneration and modulating immune responses.

The paper identifies shared expression patterns of genetic variants across tissues and cell types, enabling fine mapping of disease-associated variants and revealing key cell types involved in disease pathogenesis.