GBP1 recruitment to actin-rich pedestals induced by extracellular Gram-negative bacteria promotes pyroptosis.
Daniel J. Bennison, Ishaan Chaudhary, Dharitri Chaudhuri…·Avinash R. Shenoy
This study shows GBP1 is recruited to actin-rich pedestals formed by extracellular pathogens, promoting pyroptosis and IL-18 release, independent of LPS.