Author

Ikrame Lazar

Centre National de la Recherche ScientifiqueORCID 0000-0003-4062-3627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Aagam S. ShahiD· 1 shared Alfredo MolinoloiD· 1 shared Aline MarnefiD· 1 shared Aniruddha J. DeshpandeiD· 1 shared Anne-Laure Finoux· 1 shared Artem R CherkasoviD· 1 shared Aude Guénolé· 1 shared Benjamin Le Bozec· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Aagam S. ShahORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedNov 20, 2025

Circadian PERIOD proteins regulate TC-DSB repair through anchoring to the nuclear envelope

Benjamin Le Bozec, Laure Guitton-Sert, Sarah Collins…·Gaëlle Legube

The paper identifies PERIOD proteins as regulators of TC-DSB repair by anchoring DSBs to the nuclear envelope, linking circadian rhythms to DNA repair mechanisms.

16 citationstop 4%

humanexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 20, 2024

Targeting the translation initiation complex in therapy-resistant and metastatic melanoma

Yongmei Feng, Ximena Diaz-Olea, Xiurong Ke…·Ze’ev A. Ronai

This study identifies M19-6 as a small molecule that disrupts the eIF4F complex, reducing melanoma growth and metastasis while sparing melanocytes.

DOI 10.1101/2024.11.20.624566

humanbulk RNA-seq

𝕏 PostBluesky