Alexandros A. Pittis

This study shows that cholinergic and monoaminergic signaling originated before Bilateria, using a combination of metabolomics, phylogenetics, and single-cell analysis.

This study identifies the evolutionary origins of neurotransmitter synthesis and transport in fungi, showing these functions predate neurons and are linked to lysosomal processes in opisthokonts.

KEDROS is a web platform that performs phylogenetic profiling across proteomes to identify lineage-specific genes and functional divergence, offering a user-defined workflow for comparative genomics.

The paper examines how gene duplication shaped the evolution of the vertebrate olfactory combinatorial code by analyzing receptor-ligand interactions and ancestral sequences.

This study investigates the role of Ato proteins in carboxylic acid utilization in Candida albicans, revealing functional diversity and regulatory interactions among Ato family members.