Shoken Lee

This study identifies NPP-28 as a regulator of PLK-1 localization during mitosis, showing it partitions PLK-1 between the nuclear envelope and interior to control NEBD.

The paper identifies how amphipathic helices bind to the inner nuclear membrane by sensing lipid packing defects rather than electrostatics, showing the INM's loose packing under basal conditions.

The paper shows that hierarchical membrane-chromatin tethering, specifically involving LEM-2 and Emerin, ensures nuclear envelope stability by regulating lipid homeostasis and preventing abnormal nuclear morphology.

This study investigates the evolutionary origins and ancestral features of septins by analyzing their phylogenetic distribution and structural evolution across eukaryotes.