Targeting FSP1 triggers ferroptosis in lung cancer
Katherine Wu, Alec J. Vaughan, Jozef P. Bossowski…·Thales Y. Papagiannakopoulos
Genetic deletion or pharmacological inhibition of ferroptosis suppressor protein 1 (FSP1) induces lipid peroxidation and restricts lung adenocarcinoma growth in vivo, establishing FSP1 as a therapeutic vulnerability.