Author

Cristina H Hajdu

New York UniversityORCID 0000-0002-2856-9966Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:deep learning· 2 Assay:spatial transcriptomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1

Frequent Co-Authors

Amanda W. LundiD· 2 shared Adriana HeguyiD· 1 shared Amanda AckermanniD· 1 shared Angeliki KaratzaiD· 1 shared Anjali N. RaoiD· 1 shared Aristotelis TsirigosiD· 1 shared Ayushi S. PateliD· 1 shared Chaohui L Zhao· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Amanda W. LundORCID

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3 papers

Recent·Most cited

Cancer cell adaptations along a proliferation-robustness axis drive TME pro-tumor phenotypes

Maayan Pour, Guisheng Zhao, Angeliki Karatza, Gustavo S. França, Linda Procell, Anjali N. Rao, Deborah Corcoran, Ayushi S. Patel, Cristina H Hajdu, Kwok‐Kin Wong, Amanda W. Lund, Edna Cukierman, Itai Yanai

The paper shows cancer cells adapt along a proliferation-robustness axis in response to TME components, leading to pro-tumor phenotypes.

bioRxiv · Oct 29, 2026 · PreprintCancer Biology

Clonal Heterogeneity in Human Pancreatic Ductal Adenocarcinoma and Its Impact on Tumor Progression

Despoina Kalfakakou, Daniel C. Cameron, Emily A. Kawaler, Motoyuki Tsuda, Lidong Wang, Xiaohong Jing, Cristina H Hajdu, Dylan L. Tamayo, Yoona Shim, Amanda Ackermann, Daniel Weissinger, Hayley Zimny, Rosmel Hernandez, Matthew A. Beier, Dacia Dimartino, , Diane M. Simeone

This study analyzes clonal heterogeneity in human pancreatic ductal adenocarcinoma using single-cell and spatial transcriptomics, revealing transcriptional continua, clonal transitions, and spatially dispersed clones associated with metastasis.

bioRxiv · Feb 11, 2025 · PreprintCancer Biology

Enhanced Complement Expression in the Tumor Microenvironment Following Neoadjuvant Therapy: Implications for Immunomodulation and Survival in Pancreatic Ductal Adenocarcinoma

Xiaofei Zhang, Ruoxin Lan, Yongjun Liu, Venu Gopal Pillarisetty, Danting Li, Chaohui L Zhao, Suparna A. Sarkar, Weiguo Liu, Iman T. Hanna, Mala R. Gupta, Cristina H Hajdu, Jonathan Melamed, Jessica L. Widmer, John Allendorf, Yaozhong Liu

This study shows neoadjuvant therapy in PDAC increases complement gene expression in the tumor microenvironment, linked to better survival and reduced immune exhaustion.

bioRxiv · Oct 26, 2023 · PreprintCancer Biology