Ábel Vértesy

The paper develops COSCO to map neuronal connectivity in cerebral organoids and shows self-organizing network motifs and disease-related topological changes.

This study shows that constitutively active RAS in fission yeast prolongs Cdc42 signaling while reducing MAPK signaling through competitive binding and feedback mechanisms.

The paper uses CRISPR and single-cell transcriptomics to screen ASD risk genes in brain organoids, identifying developmental defects and regulatory modules linked to autism.

The paper identifies a stress signature in brain organoid scRNA-seq data and introduces Gruffi to remove stressed cells, improving developmental accuracy.

This study uses cerebral organoids to show that TSC2 mutations cause over-proliferation of caudal late interneuron progenitors, leading to Tuberous Sclerosis Complex.

The paper maps gene expression changes during meiotic prophase-I in mice spermatogenesis, identifying key transitions and gene regulation patterns.

The paper shows that constitutively active Ras1.G17V in S. pombe causes prolonged Cdc42 activation but only transient MAPKSpk1 activation, with a model explaining the dynamics.

The paper uses spatial transcriptomics to identify novel fertility genes in C. elegans by analyzing gene expression patterns in males and hermaphrodites.