Séverine Tabone‐Eglinger

This paper develops a method using circulating DNA fragment end motifs and machine learning to detect cancer with high accuracy across multiple cancer types.

The paper identifies 154 genes downregulated via DNMT3B-driven hypermethylation in aggressive breast cancer, including GATA3, which is inactivated through either mutations or hypermethylation, both linked to poor prognosis.