Tatsuki Tsuruoka

The paper shows that B-MYB/FOXM1 controls daughter cell fate by regulating mitotic E2F activity through timing of its activation during the cell cycle.

This paper introduces Opto-MDMi, a dual-lock optogenetic system that activates endogenous p53 with light, while suppressing basal activity in the dark.

This study develops Opto-p53, a light-controllable p53 signaling tool, to regulate p53-dependent cell fate by inducing transcriptional activation, cell death, and cell cycle arrest.