Chemical proteomics identifies signal peptidase IB (SpsB) as a target of the SOS response inhibitor OXF-077 and a regulator of quinolone resistance emergence in Staphylococcus aureus
Jacob D. Bradbury, Timothy Rutland Walsh, Thomas Lanyon‐Hogg
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Cardiff UniversityORCID 0000-0003-4315-4096Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Jacob D. Bradbury, Timothy Rutland Walsh, Thomas Lanyon‐Hogg
Kara K. Tsang, Margaret M. C. Lam, Ryan R. Wick…·KlebNET AMR Genotype-Phenotype Group
This paper reclassifies SHV β-lactamase alleles in K. pneumoniae genomes based on mutations, improving genotype-phenotype understanding and updating the Kleborate tool.
Melinda M. Ashcroft, Brian M. Forde, Minh‐Duy Phan…·Scott A. Beatson
The paper analyzes DNA methylation patterns in seven Escherichia coli ST101 strains to identify methylome diversity linked to mobile genetic elements and their impact on functional differences between nearly identical isolates.
Melinda M. Ashcroft, Brian M. Forde, Minh‐Duy Phan…·Scott A. Beatson
This study characterizes the genomic context of blaNDM-1 in E. coli ST101 isolates using long-read sequencing, revealing two clades with distinct resistance profiles and plasmid-mediated blaNDM-1 carriage mechanisms.