Masaru Miyagi

This study compares metabolic states of yeast and pseudohyphae in Malassezia furfur, showing how they differentially influence innate immune responses through extracellular metabolic environments.

This study identifies conformational signatures of non-retinoid ligands and 11-cis-retinal binding to rhodopsin using multiple techniques, revealing differential stabilization mechanisms.

This study shows that a ketogenic diet enhances the effectiveness of glutamine metabolism inhibitors in pancreatic cancer by increasing tumor reliance on glutamine for energy.

The paper develops an in vitro platform to monitor and modify caffeine metabolism linked to CYP1A2 expression using paraxanthine and qPCR.

This study shows that mutant rhodopsin causes downregulation of wild-type rhodopsin and itself, reducing light-induced damage in a mouse model of retinitis pigmentosa.

This paper uses cryo-EM with the Build-and-Retrieve method to solve integrin αIIbβ3 structures from resting human platelet membranes, revealing new insights into its regulation and dimer conformation.

This paper presents three structures of PfNCR1, a Plasmodium falciparum membrane protein, and shows it exports cholesterol to maintain membrane homeostasis, with MMV009108 inhibiting this function.