Author

Jill A. Kreiling

Brown UniversityORCID 0000-0003-4440-2039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Animal Behavior & Cognition· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:behavioral assay· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

John M. SedivyiD· 2 shared Abhirup DasiD· 1 shared Alice E. KaneiD· 1 shared Amy J. WagersiD· 1 shared Ana-Maria BaltaiD· 1 shared Attila A. SeyhaniD· 1 shared Benedito A. CarneiroiD· 1 shared Bianca Kun· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

John M. SedivyORCID

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3 papers

Recent·Most cited

Animal Behavior & CognitionBiomedicine & PharmacotherapyPeer-reviewedDec 1, 2024

Combining supervised and unsupervised analyses to quantify behavioral phenotypes and validate therapeutic efficacy in a triple transgenic mouse model of Alzheimer's disease

Thaís Del Rosario Hernández, Narendra R. Joshi, Sayali V. Gore…·Robbert Créton

The paper validates the therapeutic effects of cyclosporine A and candidate drugs in a 3xTg-AD mouse model using combined supervised and unsupervised behavioral analysis.

2 citations

mousebehavioral assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintNov 30, 2023

TRAIL pathway suppression of cancer cell growth and immune cell-mediated tumor cell-killing in a senescent fibroblast-constructed tumor microenvironment

Shengliang Zhang, Kelsey E. Huntington, Lanlan Zhou…·Wafik S. El‐Deiry

This study investigates how senescent fibroblasts influence tumor growth and immune response, showing that targeting the p21-driven SASP and combining senolytics with cancer therapies can suppress tumor growth.

DOI 10.1101/2023.11.30.569479

humanexperimental assay

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Molecular BiologybioRxivPreprintOct 21, 2019

DNA Break-Induced Epigenetic Drift as a Cause of Mammalian Aging

Motoshi Hayano, Jae-Hyun Yang, Michael S. Bonkowski…·David A. Sinclair

The paper shows that DNA double-strand breaks induce epigenomic changes that accelerate the aging clock in mammals.

24 citations

mouseDNA methylation

𝕏 PostBluesky