Author

Andrey Y. Kovalevsky

Oak Ridge National LaboratoryORCID 0000-0003-4459-9142Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Organism:bacteria (other)· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Daniel W. KnelleriD· 2 shared Alice R. WalkeriD· 1 shared Audrey D. Labbe· 1 shared B Kirtley AmosiD· 1 shared Daniel JacobsoniD· 1 shared Erica Teixeira PratesiD· 1 shared Irimpan I. MathewsiD· 1 shared Jennifer L. Clarke· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Daniel W. KnellerORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Environmental Contributions to Proton Sharing in Protein Low-Barrier Hydrogen Bonds

Jiusheng Lin, Oksana O. Gerlits, Daniel W. Kneller, Kevin L. Weiss, Leighton Coates, Jennifer L. Clarke, Mark A. Hix, Solomon Yamoah Effah, Andrey Y. Kovalevsky, Alice R. Walker, Mark A. Wilson

This study uses neutron crystallography and simulations to analyze proton sharing in low-barrier hydrogen bonds in DJ-1 and YajL, showing how mutations affect proton delocalization and mobility.

Biochemistry · Feb 9, 2026Peer-reviewedBiochemistry

Structural and functional characterization of NEMO cleavage by SARS-CoV-2 3CLpro

Mikhail A. Hameedi, Erica Teixeira Prates, Michael R. Garvin, Irimpan I. Mathews, B Kirtley Amos, Omar Demerdash, Mark Bechthold, Mamta Iyer, Simin Rahighi, Daniel W. Kneller, Andrey Y. Kovalevsky, Stephan Irle, Van‐Quan Vuong, Julie C. Mitchell, Audrey D. Labbe, , Daniel Jacobson

This study characterizes how SARS-CoV-2 3CLpro cleaves NEMO, revealing structural and functional insights that explain its high fitness in humans.

Nature Communications · Sep 8, 2022Peer-reviewedMolecular Biology