Author

Géraldine Gelders

Johnson & Johnson (United States)ORCID 0000-0003-4471-0365Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Arjan Buist· 2 shared Diederik Moechars· 2 shared Gajanan J. SatheiD· 2 shared Gopal P. SapkotaiD· 2 shared Louis De MuynckiD· 2 shared Sascha RöthiD· 2 shared Thomas MacartneyiD· 2 shared Abigail Brewer· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCell Biology

Arjan Buist

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3 papers

Recent·Most cited

Cell BiologyScientific ReportsPeer-reviewedSep 15, 2026

Data-independent acquisition (DIA) approach for comprehensive ubiquitinome profiling in targeted protein degradation

Gajanan J. Sathe, Sascha Röth, Géraldine Gelders…·Gopal P. Sapkota

This study develops a DIA-based workflow for comprehensive ubiquitinome profiling in targeted protein degradation, identifying over 40,000 ubiquitylated peptides.

DOI 10.1038/s41598-026-69423-4

humanproteomics

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NeurosciencebioRxivPreprintApr 15, 2025

Targeted degradation of α-synuclein prevents PFF-induced aggregation

Bill Carton, Géraldine Gelders, Gajanan J. Sathe…·Gopal P. Sapkota

This study demonstrates targeted degradation of α-synuclein using a nanobody-guided system, preventing PFF-induced aggregation in neurons.

2 citations

ratprotein structure

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NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedJan 6, 2021

The AppNL-G-F mouse retina is a site for preclinical Alzheimer's disease diagnosis and research

Marjan Vandenabeele, Lien Veys, Sophie Lemmens…·Lies De Groef

This study shows that the AppNL-G-F mouse retina accumulates Aβ early and exhibits AD-like features, suggesting it as a model for preclinical AD research and diagnosis.

58 citationstop 3%

mouseexperimental assay

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