Dwaipayan Adhya

This study compares mono- and bi-allelic NRXN1 mutations in iPSC-derived neurons, showing bi-allelic mutations cause more severe molecular, synaptic, and functional impairments.

This study identifies cell-type-specific DNA methylation dynamics in the human cortex across development, highlighting prenatal periods as critical for epigenomic plasticity and linking changes to neurodevelopmental disorders.

This study shows MLL2 stabilizes 3D chromatin loops during pluripotent cell differentiation without requiring its enzymatic activity.

The paper examines sex differences in brain structure at birth in newborns, finding larger brain volumes in males and specific regional differences in gray and white matter volumes between sexes.

This study investigates the impact of NRXN1 intronic deletions on early cortical development using hiPSCs, finding altered isoform expression and dendritic morphology.

This study identifies genetic correlates of phenotypic heterogeneity in autism by analyzing common and de novo variants across core features and co-occurring disabilities.

This paper optimizes Airy-beam light sheet microscopy to image 3D structures in hiPSC-derived human cortical spheroids, enabling high-resolution analysis of neurodevelopmental processes.

This study uses iPSCs from autistic individuals to identify early neurodevelopmental differences during cortical and midbrain differentiation.