David P. Corey

This study delivers GJB2 specifically to target cells in mouse models of DFNB1 deafness, restoring hearing function and validating the approach in nonhuman primates.

This paper shows that a gene therapy using a shortened PCDH15 variant rescues vision in a zebrafish model of Usher Syndrome Type 1F.

The paper shows that the auditory midbrain encodes high-frequency mechanical vibrations detected by Pacinian corpuscles, enabling behavioral responses to tactile vibrations.

The paper identifies elasticity and thermal stability as critical factors determining the effectiveness of mini-protocadherin-15 proteins in rescuing hearing in USH1F mouse models.

Hexafluoro improves visual function and reduces retinal degeneration in zebrafish models of Usher syndrome 1F by protecting photoreceptors from light-induced damage.

This paper demonstrates a dual-AAV gene therapy strategy for USH1F, restoring hearing, balance, and retinal function in mouse and human models.