Michelle M. DeLisle

The paper shows that somatosensory neuron repertoires in mammals diversify through changes to conserved neuron types, enabling adaptation to different habitats and body forms.

The paper identifies Gi/o-coupled GPCRs in nociceptors and shows that Htr1b agonists like triptans reduce neuronal excitability and pain in models, suggesting new analgesic targets.

The paper identifies A{delta}-HTMRs as fast-conducting mechanonociceptors that drive protective pain responses through unique spinal reflex circuits.

The paper shows that the auditory midbrain encodes high-frequency mechanical vibrations detected by Pacinian corpuscles, enabling behavioral responses to tactile vibrations.

This study identifies a C-LTMR-spinoparabrachial pathway that mediates wet dog shakes in mice by detecting oil droplets and triggering rapid removal of foreign particles from hairy skin.

This study uses 3D reconstructions of mechanosensory end organs to propose a unified mechanism for Aβ RA-LTMR activation through axon protrusions and Piezo2 distribution.

This study shows that γ-protocadherin isoforms are critical for synapse formation and peripheral branching in touch sensory neurons, and their loss disrupts corticospinal synapses.