John Georgiou

The paper shows that spaced theta-burst stimulation enhances synaptic potentiation in the prefrontal cortex of socially isolated mice.

The paper characterizes a Grin1Q536R/+ mouse model carrying a GRIN1 variant, showing age- and sex-dependent behavioral and physiological changes linked to GRIN1-NDD.

The paper examines microglial phagocytic activity and morphology across hippocampal subregions during development, finding subregion-specific changes in microglial phenotype in early adulthood.

The paper demonstrates that CP-AMPAR activation is essential for both homosynaptic and heterosynaptic structural LTP in hippocampal slices, with heterosynaptic LTP showing faster development and trans-synaptic interactions.

This study shows that tau deletion enhances synaptic weakening in male rats but not females, revealing sex-dependent effects on synaptic function and actin dynamics.

This study investigates the role of group I mGluRs in synaptic tagging and capture (STC) in mouse hippocampus, showing their requirement for heterosynaptic priming of long-term potentiation.

This study investigates the effects of the GRIN1 Y647S variant in mice, showing that β-hydroxybutyrate reduces convulsions associated with the variant.

The paper provides pharmacological evidence supporting the role of CP-AMPARs in synaptic tag and capture at hippocampal CA1 synapses through experimental validation of predicted effects.

The paper shows that LTP in hippocampal synapses can increase AMPA receptor number or conductance, with distinct mechanisms involving CaMKII and PKA.