Author

Megan T. Sullivan

University of Toronto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:electronic health records· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Amy J. RamseyiD· 3 shared Evelyn K. LambeiD· 3 shared Sridevi VenkatesaniD· 3 shared Ali SalahpouriD· 2 shared Graham L. CollingridgeiD· 2 shared John GeorgiouiD· 2 shared Patrick TidballiD· 2 shared Peter S.B. FinnieiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Amy J. RamseyORCID

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Author profile →

3 papers

Recent·Most cited

Characterization of the Grin1Q536R/+ mouse: a preclinical model for GRIN1-related neurodevelopmental disorder

Megan T. Sullivan, Yuanye Yan, Lyra Vania, Patrick Tidball, Quinn Pauli, Tatiana V. Lipina, Sridevi Venkatesan, Peter S.B. Finnie, Emily Fujiwara, Wendy Horsfall, John Georgiou, Robert Erne McCullumsmith, Evelyn K. Lambe, Robert P. Bonin, Ali Salahpour, , Amy J. Ramsey

The paper characterizes a Grin1Q536R/+ mouse model carrying a GRIN1 variant, showing age- and sex-dependent behavioral and physiological changes linked to GRIN1-NDD.

bioRxiv · Sep 15, 2026 · PreprintNeuroscience

Context-dependent NMDA receptor dysfunction predicts seizure treatment in mice with human GluN1 variant

Sridevi Venkatesan, Daria Nazarkina, Megan T. Sullivan, Yao‐Fang Tan, Sarah Qu, Amy J. Ramsey, Evelyn K. Lambe

The paper shows that a GluN1 variant causes NMDAR dysfunction in mice, leading to seizures, and demonstrates that boosting negative feedback can treat them.

iScience · Dec 1, 2025Peer-reviewedNeuroscience

β-hydroxybutyrate improves convulsions in mice carrying the GRIN1 Y647S/+ pathogenic variant

Megan T. Sullivan, Patrick Tidball, Yuanye Yan, Katheron Intson, Wenjuan Chen, Yuchen Xu, Sridevi Venkatesan, Wendy Horsfall, John Georgiou, Peter S.B. Finnie, Robert E. McCullumsmith, Evelyn K. Lambe, Stephen F. Traynelis, Ali Salahpour, Hongjie Yuan, , Amy J. Ramsey

This study investigates the effects of the GRIN1 Y647S variant in mice, showing that β-hydroxybutyrate reduces convulsions associated with the variant.

bioRxiv · Aug 21, 2024 · PreprintNeuroscience