Gabriel Torregrosa-Cortés

This study shows retinoic acid signaling regulates the anterior-to-posterior transition in mesoderm development by modulating Wnt signaling and T-box factors.

This paper introduces a 3D hemogenic gastruloid model to study infant acute myeloid leukemia origins, showing MNX1-driven transformation of erythroid-myeloid progenitors.

The paper identifies HSP90 inhibitors as potential therapies for t(7;12)-AML by combining computational drug screening with in vitro experiments.

This study shows that Nodal and Wnt signalling act antagonistically during mammalian gastrulation, with Nodal promoting anterior structures and Wnt driving posterior development.

The paper shows that collective cell fate decisions and mechanical differences drive symmetry breaking in gastruloids through a mechanochemical mechanism.

This study investigates how size affects morphogenesis and transcriptional profiles in mouse gastruloids, revealing size-dependent changes in axial elongation and tissue composition.

This paper introduces a Bayesian deconvolution method to separate signal from noise in single-cell measurements, applied to study Brachyury expression in differentiating mouse embryonic stem cells.