Author

Ayona Johns

Brunel University of London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Chun-Wai Wade SueniD· 2 shared Cristina PinaiD· 2 shared Denise RagusaiD· 2 shared Gabriel Torregrosa-CortésiD· 2 shared Ylenia CiciròiD· 2 shared Alfonso Martínez AriasiD· 1 shared Alice GiustacchiniiD· 1 shared Anna BigasiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersDevelopmental Biology

Chun-Wai Wade SuenORCID

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2 papers

Recent·Most cited

Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

Denise Ragusa, Chun-Wai Wade Suen, Gabriel Torregrosa-Cortés, Fabio Pastorino, Ayona Johns, Ylenia Cicirò, Liza Dijkhuis, Susanne van den Brink, Michele Cilli, Connor Byrne, Giulia-Andreea Ionescu, Joana Cerveira, Kamil R. Kranc, Víctor Hernández-Hernández, Mirco Ponzoni, , Cristina Pina

This paper introduces a 3D hemogenic gastruloid model to study infant acute myeloid leukemia origins, showing MNX1-driven transformation of erythroid-myeloid progenitors.

eLife · Sep 11, 2025Peer-reviewedDevelopmental Biology

Integrated in silico and in vitro approaches identify a HSP90 drug vulnerability axis in t(7;12) infant leukemia stem-like cells

Ylenia Cicirò, Denise Ragusa, Emily M. Johnson, Ayona Johns, Sina Kanannejad, Remisha Gurung, Macarena Oporto Espuelas, Chun-Wai Wade Suen, Gabriel Torregrosa-Cortés, Alice Giustacchini, Sabrina Tosi, Cristina Pina

The paper identifies HSP90 inhibitors as potential therapies for t(7;12)-AML by combining computational drug screening with in vitro experiments.

bioRxiv · Sep 6, 2025 · PreprintCancer Biology