Nicola Brice

This study uses NETSseq to analyze cerebellar tissue from A-T patients and controls, identifying cell-type-specific gene dysregulation and aging signatures linked to neurological decline.

This study identifies a novel target for obesity treatment by showing that inhibiting GABAergic neurons in the dorsal raphe nucleus reduces body weight in diet-induced obese mice through thermogenesis.

This study shows SIPA1L2 connects TrkB-containing amphisomes to dynein for retrograde trafficking and local signaling at presynaptic terminals, essential for BDNF-dependent plasticity.