Author

Mark B. L. Carlton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Nicola BriceiD· 3 shared Daniel F. BarkeriD· 2 shared Keith J. PageiD· 2 shared Aiste BaleisyteiD· 1 shared Alexandre Moura‐AssisiD· 1 shared Anna KarpovaiD· 1 shared Antonio Virgilio FaillaiD· 1 shared Bandy Chen· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersNeuroscience

Nicola BriceORCID

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3 papers

Recent·Most cited

NETSseq Reveals Inflammatory and Aging Mechanisms in Distinct Cell Types Driving Cerebellar Decline in Ataxia Telangiectasia

Giuliano Giuseppe Stirparo, Xiao Xu, Thompson Toni, Keith J. Page, Jenna R. M. Harvey, David Cadwalladr, Jason M.K. Lawrence, Russell Burley, Joel Juvvanapudi, Roberts Megan, Daniel F. Barker, Victoria J. Mulligan, Sherlock Chloe, Marina Lizio, Louisa A. Christie, , Lee A. Dawson

This study uses NETSseq to analyze cerebellar tissue from A-T patients and controls, identifying cell-type-specific gene dysregulation and aging signatures linked to neurological decline.

bioRxiv · May 13, 2025 · PreprintNeuroscience

Identification of a Thermogenic Target in the Dorsal Raphe Nucleus for Weight Management

Alexandre Moura‐Assis, Kaja Plucińska, Aiste Baleisyte, David Meseguer, Bandy Chen, Kyle Pellegrino, Luca Parolari, Jordan T. Shaked, Keith J. Page, Douglas W. Barrows, Thomas S. Carroll, Jose G. Grajales‐Reyes, Daxiang Na, Hans H. Schiffer, Yun Chen, , Marc Schneeberger

This study identifies a novel target for obesity treatment by showing that inhibiting GABAergic neurons in the dorsal raphe nucleus reduces body weight in diet-induced obese mice through thermogenesis.

bioRxiv · Apr 24, 2025 · PreprintNeuroscience

SIPA1L2 controls trafficking and signaling of TrkB-containing amphisomes at presynaptic terminals

Maria Andres‐Alonso, Mohamed Raafet Ammar, Ioana Butnaru, Guilherme M. Gomes, Gustavo Acuña Sanhueza, Rajeev Raman, PingAn Yuanxiang, Maximilian Borgmeyer, Jeffrey Lopez‐Rojas, Syed Ahsan Raza, Nicola Brice, Torben Johann Hausrat, Tamar Macharadze, Silvia Diaz-Gonzalez, Mark B. L. Carlton, , Michael R. Kreutz

This study shows SIPA1L2 connects TrkB-containing amphisomes to dynein for retrograde trafficking and local signaling at presynaptic terminals, essential for BDNF-dependent plasticity.

Nature Communications · Nov 29, 2019Peer-reviewedNeuroscience