Author

Paula V. Schiapparelli

Mayo ClinicORCID 0000-0003-4551-6337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alfredo Quiñones‐HinojosaiD· 2 shared Rachel Whitehead· 2 shared Steven S. RosenfeldiD· 2 shared Aleeshba N. BasiliD· 1 shared Alfredo Quinones Hinojosa· 1 shared Annalisa M. Hartlaub· 1 shared Asha Nair· 1 shared Brianna Tapia-Dierking· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Alfredo Quiñones‐HinojosaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 19, 2026

Intracranial Targeting of Cholesterol Processing Reveals a Therapeutic Vulnerability that Reprograms Glioblastoma and Promotes Antitumor Immunity

María José Ulloa-Navas, Rachel Whitehead, Vanessa K. Jones…·Alfredo Quiñones‐Hinojosa

This study identifies cholesterol dependency as a therapeutic target in glioblastoma, showing that combined treatment with clemastine and bexarotene induces metabolic collapse and enhances antitumor immunity.

DOI 10.64898/2026.08.18.745568

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintNov 3, 2024

Inhibition of Yes-Associated Protein (YAP) with Verteporfin Enhances Radiosensitivity in Chordoma by Inducing G2M Arrest and Inhibiting the DNA Damage Response

Oluwaseun Oluwadara Akinduro, Paola Suarez Meade, Paula V. Schiapparelli…·Alfredo Quinones Hinojosa

This study shows that YAP inhibition with verteporfin increases radiosensitivity in chordoma by blocking DNA repair and causing G2M arrest.

DOI 10.1101/2024.11.03.621728

mousebulk RNA-seq

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NeurosciencePNAS NexusPeer-reviewedFeb 1, 2024

Patient-Derived Organoids Recapitulate Intrinsic Immune Landscapes and Progenitor Populations of Glioblastoma.

Fumihiro Watanabe, Ethan W. Hollingsworth, Jenna M. Bartley…·Jaime Imitola

The paper characterizes GSC-derived GBM organoids, revealing an immune-like molecular program and identifying SATB2+ and HOPX+ progenitor populations that contribute to GBM progression.

24 citationstop 3%

humanbulk RNA-seq

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