Author

Dylan G. Ryan

University of CambridgeORCID 0000-0003-4553-9192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Adam GołȩbiowskiiD· 1 shared Adam Konrad JagielskiiD· 1 shared Alex von KriegsheimiD· 1 shared Alva M. CaseyiD· 1 shared Angelika MuchowicziD· 1 shared Arthur KaseriD· 1 shared Barbara DymekiD· 1 shared Bartłomiej HofmaniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Adam GołȩbiowskiORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyFrontiers in ImmunologyPeer-reviewedMay 29, 2025

Chitinase-1 inhibition reverses metabolic dysregulation and restores homeostasis in MASH animal models

Katarzyna Drzewicka, Katarzyna Głuchowska, Michał Mlącki…·Zbigniew Zasłona

This study shows that inhibiting chitinase-1 with OATD-01 reverses metabolic dysregulation and restores homeostasis in MASH animal models.

4 citations

𝕏 PostBluesky

ImmunologybioRxivPreprintJan 5, 2025

An inherited mtDNA mutation remodels inflammatory cytokine responses in macrophages and in vivo

Eloïse Marques, Stephen P. Burr, Alva M. Casey…·Dylan G. Ryan

This study shows that an inherited mtDNA mutation alters inflammatory cytokine responses in macrophages and in vivo, leading to increased IFN-I and reduced pro-inflammatory cytokines.

1 citation

mousemetabolomics

𝕏 PostBluesky