Author

Rui Guo

Brigham and Women's HospitalORCID 0000-0003-4584-1324Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Rui Guo11 papers · Fujian Agriculture and Forestry University

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Benjamin E. GewurziD· 2 shared A. NairiD· 1 shared Allyssa L. DaughertyiD· 1 shared Alvin Huang· 1 shared Andrew M. SorniD· 1 shared Bo ZhaoiD· 1 shared Carmy R. ForneyiD· 1 shared Chong WangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Benjamin E. GewurzORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintSep 28, 2026

A Human Genome-wide CRISPR-Cas9 Screen Reveals Host Factors That Support Epstein-Barr Virus B cell infection

Hongbo Wang, Yao Yu Yeo, Chong Wang…·Bo Zhao

This study uses a genome-wide CRISPR-Cas9 screen to identify host factors essential for EBV B cell infection, revealing new pathways and potential therapeutic targets.

DOI 10.64898/2026.09.28.754942

humangenetic perturbation / CRISPR

𝕏 PostBluesky

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedAug 13, 2026

A tonsil organoid model reveals Epstein-Barr virus infected germinal center B cell states during primary infection

Mahina Tabassum Mitul, Yizhe Sun, Timothy B. Yates…·Lisa E. Wagar

This study develops an EBV-infected tonsil organoid model to study B cell states and antiviral responses during primary infection, revealing unique transcriptional programs and immune interactions.

DOI 10.1073/pnas.2603586123

humanorganoid / primary culture

𝕏 PostBluesky