Christopher G. Bell

The paper develops AI models to predict enhancers in human and mouse cell lines, identifying H3K18ac as a new enhancer marker and annotating enhancers using a combination of epigenetic marks.

The paper identifies ultra-conserved CpGs associated with ageing-related methylation changes and developmental pathways in the brain.

This study shows that sub-chronic stress causes hypomethylation of the Fkbp5 promoter, increasing chronic pain vulnerability, but reversing this methylation does not prevent pain.

This study investigates epigenomic changes in left and right atria of atrial fibrillation patients compared to controls, identifying dysregulated loci and epigenetic mechanisms.

The paper integrates genetic fine-mapping with multi-omics data to identify candidate effector genes and new drug targets for hypertension.

The paper investigates the DNA methylation profile of FKBP5 in chronic pain models, finding significant differences between pain states and correlations between CNS and blood methylation, suggesting FKBP5 as a potential biomarker for chronic pain diagnosis and vulnerability prediction.

The paper identifies age-related DNA hypermethylation at specific human tRNA gene loci using DNA methylome data from peripheral blood.

The paper integrates chromatin accessibility and DNA methylation data from human pancreatic islets to refine regulatory mechanisms at Type 2 Diabetes susceptibility loci.