Author

Arun S. Annamalai

University of Colorado AnschutzORCID 0000-0003-4672-7283Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

Alan EngelmaniD· 2 shared Ashwanth Christopher FrancisiD· 2 shared Juliet Greenwood· 2 shared Lorenzo BrigantiiD· 2 shared Mamuka KvaratskheliaiD· 2 shared Reed Haney· 2 shared Satya Prakash SinghiD· 2 shared Szu‐Wei HuangiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

Alan EngelmanORCID

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2 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedApr 15, 2025

Structural and Mechanistic Bases for Resistance of the M66I Capsid Variant to Lenacapavir

Lorenzo Briganti, Arun S. Annamalai, Stephanie M. Bester…·Mamuka Kvaratskhelia

This paper investigates how the M66I mutation in HIV-1 capsid protein confers resistance to lenacapavir by altering inhibitor binding and viral replication.

23 citationstop 1%

humanstructural biology

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MicrobiologyPLoS PathogensPeer-reviewedJan 27, 2025

The primary mechanism for highly potent inhibition of HIV-1 maturation by lenacapavir

Szu‐Wei Huang, Lorenzo Briganti, Arun S. Annamalai…·Mamuka Kvaratskhelia

This study identifies the mechanism by which lenacapavir inhibits HIV-1 maturation by altering capsid protein assembly.

26 citationstop 1%

humanproteomics

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