Author

Susan Bonner‐Weir

Harvard UniversityORCID 0000-0003-4682-0656Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Siying WeiiD· 2 shared Yi PengiD· 2 shared Alexander Lee-Papastavros· 1 shared Andy Ma· 1 shared Birgitta A. RybackiD· 1 shared Brooke Sullivan· 1 shared Bryhan Mendez· 1 shared Claudiane GuayiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPhysiology

Siying WeiORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintDec 18, 2025

Small non-coding RNA profiling reveals inflammatory and mitochondrial related changes in aging β-cells and islet macrophages

Claudiane Guay, Jérôme Perrard, Eleonora Mangano…·Romano Regazzi

This study profiles small non-coding RNAs in aging β-cells and islet macrophages, identifying age-related changes in miRNAs and tRFs linked to inflammation and mitochondrial function.

DOI 10.64898/2025.12.17.694889

mousestatistical model

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PhysiologyMolecular MetabolismPeer-reviewedFeb 21, 2025

Renalase inhibition regulates β cell metabolism to defend against acute and chronic stress

Tara L. MacDonald, Birgitta A. Ryback, Jéssica Aparecida da Silva Pereira…·Yi Peng

This study shows that inhibiting Renalase protects β cells from stress by shifting metabolism towards glycolysis and GSH synthesis in both mice and humans.

8 citations

mousehuman

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GeneticsbioRxivPreprintMay 13, 2024

Loss-of-function of ALDH3B2 transdifferentiates human pancreatic duct cells into beta-like cells

Jian Li, Kevin Bode, Yu‐Chi Lee…·Yi Peng

This study shows that knocking out ALDH3B2 in human pancreatic duct cells converts them into beta-like cells that function and reduce blood glucose in mice.

DOI 10.1101/2024.05.13.593941

humanCRISPR screen

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