Author

Chiara Lasconi

Children's Hospital of PhiladelphiaORCID 0000-0003-4684-704XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:ATAC-seq· 2 Research Focus:gene regulatory network inference· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alessandra ChesiiD· 3 shared Andrew D. WellsiD· 3 shared James A. PippiniD· 3 shared Struan F.A. GrantiD· 3 shared Alex C. KeeneiD· 2 shared Allan I PackiD· 2 shared Amber J. ZimmermaniD· 2 shared Elizabeth BrowniD· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Alessandra ChesiORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintAug 17, 2023

Perturbation of the insomnia WDR90 GWAS locus pinpoints rs3752495 as a causal variant influencing distal expression of neighboring gene, PIG-Q

Shilpa Sonti, Sheridan H. Littleton, Matthew C. Pahl…·Struan F.A. Grant

This study identifies rs3752495 as the causal variant at the insomnia WDR90 GWAS locus that influences PIG-Q expression through a regulatory mechanism.

1 citation

humanATAC-seq

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GeneticsScience AdvancesPeer-reviewedJan 6, 2023

Variant-to-gene-mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as novel regulator of sleep

Justin Palermo, Alessandra Chesi, Amber J. Zimmerman…·Alex C. Keene

The paper identifies GPI-anchor biosynthesis as a conserved regulator of sleep through variant-to-gene mapping and cross-species genetic screening in humans and model organisms.

49 citationstop 2%

humanDrosophila

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GenomicsNature CommunicationsPeer-reviewedNov 19, 2021

Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant common complex traits

Matthew C. Pahl, Claudia A. Doege, Kenyaita M. Hodge…·Struan F.A. Grant

The paper maps cis-regulatory elements in human ESC-derived hypothalamic neurons and links them to GWAS loci for complex traits, identifying candidate genes and regulatory elements involved in hypothalamic development.

46 citations

humanChIP-seq

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