SRF fusion oncogenes encode constitutively activated chimeric transcription factors in myoid soft tissue tumors
Constance Pirson, Ariane Sablon, Axelle E. Loriot…·Jean‐Baptiste Demoulin
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Lyon 1 UniversitéORCID 0000-0003-4731-7817Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Constance Pirson, Ariane Sablon, Axelle E. Loriot…·Jean‐Baptiste Demoulin
Gaëlle Pérot, Clémence Guerriau, Natacha Roussel…·Frédéric Chibon
The paper investigates the relationship between alternative lengthening of telomeres (ALT) and the CINSARC signature in non-translocation-related sarcomas, showing their strong association.
Elamine Zereg, Laure Voisin, Mathieu Courcelles…·Sylvain Meloche
This study identifies YES and SRC tyrosine kinases as redundant drivers of MPNST and shows their inhibition suppresses tumor growth and reactivates immune responses.
Daniel Aldea, Sarah Guégan, Israa Fakih…·Heather Etchevers
This study maps spatially resolved molecular states in congenital melanocytic nevi and associated tumors, revealing distinct melanocyte subpopulations and signaling networks linked to disease progression.