Mathieu Courcelles

This study identifies YES and SRC tyrosine kinases as redundant drivers of MPNST and shows their inhibition suppresses tumor growth and reactivates immune responses.

The paper provides detailed experimental protocols and an open-source tool, MhcVizPipe, for analyzing MHC I and II ligand datasets in immunopeptidomics.

The paper introduces CAMAP, an artificial neural network that predicts MHC-I peptide presentation by analyzing codon arrangement in mRNA sequences, improving prediction accuracy beyond traditional methods.