Dale George

This study develops a novel method to generate human induced pluripotent stem cell-derived sensory neurons that closely resemble primary human tissue transcriptionally and functionally.

This study identifies epidermal Langerhans cells as key contributors to painful diabetic neuropathy, revealing sex-dependent roles in mechanical allodynia and pain behavior.

The paper identifies Mrgprd-expressing DRG neurons as a driver of pain hypersensitivity in a mouse model of PDN and shows targeting these neurons can reverse mechanical allodynia.

This study identifies the cellular distribution of matrisome genes in murine and human dorsal root ganglia, revealing their potential role in neuronal signaling and pain.