Nils Opel

The paper examines how childhood maltreatment affects brain structure in 3,711 individuals with MDD and PTSD, finding age- and sex-specific brain morphometric differences.

This study investigates the replicability of gray matter correlates of childhood maltreatment across three cohorts and finds no significant replication after controlling for depression.

This study shows that spermidine supplementation improves depression symptoms by enhancing autophagy and correcting polyamine imbalances in both humans and mice.

This paper investigates how cross-validation affects effect size estimation in brain-wide association studies and finds that cross-validation improves generalizability, especially in small samples.

The paper investigates how molecular and connectomic vulnerabilities contribute to cortical abnormalities across multiple brain disorders using MRI data from 47,000 individuals.

This study identifies genetic variants linked to longitudinal brain structure changes across the lifespan using MRI data from 15,640 individuals.

This study identifies subcortical shape differences in MDD patients using ENIGMA data, highlighting region-specific changes in surface area and thickness.

This study finds that higher HbA1c levels are associated with worse cognitive performance and reduced white matter integrity in healthy young adults.